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Transcriptional and posttranscriptional regulation of the SMC-selective blood pressure-associated gene, ARHGAP42

We previously showed that ARHGAP42 is a smooth muscle cell (SMC)-selective, RhoA-specific GTPase activating protein that regulates blood pressure and that a minor allele single nucleotide variation within a DNAse hypersensitive regulatory element in intron1 (Int1DHS) increased ARHGAP42 expression by...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Mangum, Kevin D., Freeman, Emily J., Magin, Justin C., Taylor, Joan M., Mack, Christopher P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052622/
https://ncbi.nlm.nih.gov/pubmed/31886719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00143.2019
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