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Accelerated cardiomyocyte senescence contributes to late-onset doxorubicin-induced cardiotoxicity

Children surviving cancer and chemotherapy are at risk for adverse health events including heart failure that may be delayed by years. Although the early effects of doxorubicin-induced cardiotoxicity may be attributed to a direct effect on the cardiomyocytes, the mechanisms underlying the delayed or...

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Détails bibliographiques
Publié dans:Am J Physiol Cell Physiol
Auteurs principaux: Mitry, Maria A., Laurent, Dimitri, Keith, Britny L., Sira, Elizabeth, Eisenberg, Carol A., Eisenberg, Leonard M., Joshi, Sachindra, Gupte, Sachin, Edwards, John G.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052608/
https://ncbi.nlm.nih.gov/pubmed/31913702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00073.2019
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