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α-Synuclein Translocates to the Nucleus to Activate Retinoic-Acid-Dependent Gene Transcription
α-Synuclein (α-Syn) protein is implicated in the pathogenesis of Parkinson disease (PD). It is primarily cytosolic and interacts with cell membranes. α-Syn also occurs in the nucleus. Here we investigated the mechanisms involved in nuclear translocation of α-Syn. We analyzed alterations in gene expr...
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| Publicat a: | iScience |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7052517/ https://ncbi.nlm.nih.gov/pubmed/32120069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.100910 |
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