A role for α-Synuclein in axon growth and its implications in corticostriatal glutamatergic plasticity in Parkinson’s disease

BACKGROUND: α-Synuclein (α-Syn) is a protein implicated in the pathogenesis of Parkinson’s disease (PD). α-Syn has been shown to associate with membranes and bind acidic phospholipids. However, the physiological importance of these associations to the integrity of axons is not fully clear. METHODS:...

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Publicat a:Mol Neurodegener
Autors principals: Schechter, Meir, Grigoletto, Jessica, Abd-Elhadi, Suaad, Glickstein, Hava, Friedman, Alexander, Serrano, Geidy E., Beach, Thomas G., Sharon, Ronit
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7104492/
https://ncbi.nlm.nih.gov/pubmed/32228705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-020-00370-y
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