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Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury
Mannose-binding lectin (MBL), an initiator of the lectin pathway (LP) of complement activation, is detrimental in ischemic stroke, as shown in clinical studies and rodent models. Whereas humans have one functional MBL protein, rodents have two isoforms, MBL-A and MBL-C, whose functions relative to t...
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| Veröffentlicht in: | Cell Mol Immunol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7052250/ https://ncbi.nlm.nih.gov/pubmed/30967639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-019-0225-1 |
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