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Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury

Mannose-binding lectin (MBL), an initiator of the lectin pathway (LP) of complement activation, is detrimental in ischemic stroke, as shown in clinical studies and rodent models. Whereas humans have one functional MBL protein, rodents have two isoforms, MBL-A and MBL-C, whose functions relative to t...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Neglia, Laura, Oggioni, Marco, Mercurio, Domenico, De Simoni, Maria-Grazia, Fumagalli, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052250/
https://ncbi.nlm.nih.gov/pubmed/30967639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-019-0225-1
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