Mannose-Binding Lectin Drives Platelet Inflammatory Phenotype and Vascular Damage After Cerebral Ischemia in Mice via IL (Interleukin)-1α

OBJECTIVE—: Circulating complement factors are activated by tissue damage and contribute to acute brain injury. The deposition of MBL (mannose-binding lectin), one of the initiators of the lectin complement pathway, on the cerebral endothelium activated by ischemia is a major pathogenic event leadin...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Orsini, Franca, Fumagalli, Stefano, Császár, Eszter, Tóth, Krisztina, De Blasio, Daiana, Zangari, Rosalia, Lénárt, Nikolett, Dénes, Ádám, De Simoni, Maria-Grazia
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2018
Assuntos:
Basic Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6221395/
https://ncbi.nlm.nih.gov/pubmed/30354247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.311058
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