Mannose-Binding Lectin Drives Platelet Inflammatory Phenotype and Vascular Damage After Cerebral Ischemia in Mice via IL (Interleukin)-1α

OBJECTIVE—: Circulating complement factors are activated by tissue damage and contribute to acute brain injury. The deposition of MBL (mannose-binding lectin), one of the initiators of the lectin complement pathway, on the cerebral endothelium activated by ischemia is a major pathogenic event leadin...

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Enregistré dans:
Détails bibliographiques
Publié dans:Arterioscler Thromb Vasc Biol
Auteurs principaux: Orsini, Franca, Fumagalli, Stefano, Császár, Eszter, Tóth, Krisztina, De Blasio, Daiana, Zangari, Rosalia, Lénárt, Nikolett, Dénes, Ádám, De Simoni, Maria-Grazia
Format: Artigo
Langue:Inglês
Publié: Lippincott Williams & Wilkins 2018
Sujets:
Basic Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6221395/
https://ncbi.nlm.nih.gov/pubmed/30354247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.311058
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