The LRRK2 N-terminal domain influences vesicle trafficking: impact of the E193K variant

The LRRK2 protein consists of multiple functional domains, including protein-binding domains at its N and C-terminus. Mutations in the Leucine-rich repeat kinase 2 gene (LRRK2) have been linked to familial and sporadic Parkinson’s disease (PD). We have recently described a novel variant falling with...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Marku, Algerta, Carrion, Maria Dolores Perez, Pischedda, Francesca, Marte, Antonella, Casiraghi, Zeila, Marciani, Paola, von Zweydorf, Felix, Gloeckner, Christian Johannes, Onofri, Franco, Perego, Carla, Piccoli, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052203/
https://ncbi.nlm.nih.gov/pubmed/32123243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60834-5
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados