Regulation of the linear ubiquitination of STAT1 controls antiviral interferon signaling

Linear ubiquitination is a critical regulator of inflammatory signaling pathways. However, linearly ubiquitinated substrates and the biological significance of linear ubiquitination is incompletely understood. Here, we show that STAT1 has linear ubiquitination at Lys511 and Lys652 residues in intact...

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Publicado en:Nat Commun
Main Authors: Zuo, Yibo, Feng, Qian, Jin, Lincong, Huang, Fan, Miao, Ying, Liu, Jin, Xu, Ying, Chen, Xiangjie, Zhang, Hongguang, Guo, Tingting, Yuan, Yukang, Zhang, Liting, Wang, Jun, Zheng, Hui
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052135/
https://ncbi.nlm.nih.gov/pubmed/32123171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14948-z
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