Characterization of a potent and highly unusual minimally-enhancing antibody directed against dengue virus

Dengue virus is a major pathogen and severe infections can lead to life threatening dengue hemorrhagic fever (DHF). Dengue exists as four serotypes and DHF is often associated with secondary heterologous infections. Antibody dependent enhancement (ADE) may drive higher virus loads in these secondary...

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Gepubliceerd in:Nat Immunol
Hoofdauteurs: Renner, Max, Flanagan, Aleksandra, Dejnirattisai, Wanwisa, Puttikhunt, Chunya, Kasinrerk, Watchara, Supasa, Piyada, Wongwiwat, Wiyada, Chawansuntati, Kriangkrai, Duangchinda, Thaneeya, Cowper, Alison, Midgley, Claire M, Malasit, Prida, Huiskonen, Juha T., Mongkolsapaya, Juthathip, Screaton, Gavin R., Grimes, Jonathan M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7051845/
https://ncbi.nlm.nih.gov/pubmed/30323338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-018-0227-7
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