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Structural analysis of a dengue cross-reactive antibody complexed with envelope domain III reveals the molecular basis of cross-reactivity()

Dengue virus infections are still increasing at an alarming rate in tropical and subtropical countries underlying the need for a dengue vaccine. Although it is relatively easy to generate antibody responses to dengue virus, low avidity or low concentrations of antibody may enhance infection of Fc re...

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Detalhes bibliográficos
Main Authors: Midgley, Claire M., Flanagan, Aleksandra, Tran, Hai Bac, Dejnirattisai, Wanwisa, Chawansuntati, Kriangkrai, Jumnainsong, Amonrat, Wongwiwat, Wiyada, Duangchinda, Thaneeya, Mongkolsapaya, Juthathip, Grimes, Jonathan M., Screaton, Gavin R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364712/
https://ncbi.nlm.nih.gov/pubmed/22491255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200227
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