Enhancing cross-reactive anti-prM dominates the human antibody response in dengue infection

Dengue virus co-circulates as four serotypes and sequential infections with more than one serotype are common. One hypothesis for the increased severity seen in secondary infections is antibody dependent enhancement (ADE) leading to increased replication in Fc-receptor-bearing cells. In this study w...

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Autores principales: Dejnirattisai, Wanwisa, Jumnainsong, Amonrat, Onsirisakul, Naruthai, Fitton, Patricia, Vasanawathana, Sirijitt, Limpitikul, Wannee, Puttikhunt, Chunya, Edwards, Carolyn, Duangchinda, Thaneeya, Supasa, Sunpetchuda, Chawansuntati, Kriangkrai, Malasit, Prida, Mongkolsapaya, Juthathip, Screaton, Gavin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837288/
https://ncbi.nlm.nih.gov/pubmed/20448183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1185181
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