Enhancing cross-reactive anti-prM dominates the human antibody response in dengue infection

Dengue virus co-circulates as four serotypes and sequential infections with more than one serotype are common. One hypothesis for the increased severity seen in secondary infections is antibody dependent enhancement (ADE) leading to increased replication in Fc-receptor-bearing cells. In this study w...

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Bibliografiske detaljer
Main Authors:	Dejnirattisai, Wanwisa, Jumnainsong, Amonrat, Onsirisakul, Naruthai, Fitton, Patricia, Vasanawathana, Sirijitt, Limpitikul, Wannee, Puttikhunt, Chunya, Edwards, Carolyn, Duangchinda, Thaneeya, Supasa, Sunpetchuda, Chawansuntati, Kriangkrai, Malasit, Prida, Mongkolsapaya, Juthathip, Screaton, Gavin
Format:	Artigo
Sprog:	Inglês
Udgivet:	2010
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3837288/ https://ncbi.nlm.nih.gov/pubmed/20448183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1185181
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Enhancing cross-reactive anti-prM dominates the human antibody response in dengue infection

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