Oncolytic poxvirus CF33-hNIS-ΔF14.5 favorably modulates tumor immune microenvironment and works synergistically with anti-PD-L1 antibody in a triple-negative breast cancer model

Triple-negative breast cancer is the most aggressive subtype of breast cancer and is difficult to treat. Breast cancer is considered to be poorly immunogenic and hence is less responsive to immunotherapies. We tested whether the oncolytic poxvirus CF33-hNIS-ΔF14.5 could modulate tumor immune microen...

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Publicado en:Oncoimmunology
Main Authors: Chaurasiya, Shyambabu, Yang, Annie, Kang, Seonah, Lu, Jianming, Kim, Sang-In, Park, Anthony K., Sivanandam, Venkatesh, Zhang, Zhifang, Woo, Yanghee, Warner, Susanne G., Fong, Yuman
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2020
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7051185/
https://ncbi.nlm.nih.gov/pubmed/32158622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1729300
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