MicroRNA124-IL6R Mediates the Effect of Nicotine in Inflammatory Bowel Disease by Shifting Th1/Th2 Balance Toward Th1

Epidemiological investigations have shown that smoking ameliorates ulcerative colitis (UC) but exacerbates Crohn's disease (CD), diseases that feature a Th2-mediated and Th1-mediated response, respectively. Cigarette extracts, especially nicotine, affect the Th1/Th2 balance. We previously repor...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Qin, Zhen, Wang, Peng-Yuan, Wan, Jing-Jing, Zhang, Yu, Wei, Jie, Sun, Yang, Liu, Xia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050625/
https://ncbi.nlm.nih.gov/pubmed/32153570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00235
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