Myricetin Possesses Anthelmintic Activity and Attenuates Hepatic Fibrosis via Modulating TGFβ1 and Akt Signaling and Shifting Th1/Th2 Balance in Schistosoma japonicum-Infected Mice

Schistosomiasis is a zoonotic and debilitating parasitic disease caused by Schistosoma japonicum. Praziquantel remains the choice for treating schistosomiasis, but its efficacy could be hampered by emergence of resistance. In this study, using large-scale drug screening, we selected out myricetin, a...

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Foilsithe in:Front Immunol
Main Authors: Huang, Ping, Zhou, Minyu, Cheng, Shaoyun, Hu, Yue, Gao, Minzhao, Ma, Yubin, Limpanont, Yanin, Zhou, Hongli, Dekumyoy, Paron, Cheng, Yixin, Lv, Zhiyue
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2020
Ábhair:
Immunology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176910/
https://ncbi.nlm.nih.gov/pubmed/32373112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00593
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