Myricetin Possesses Anthelmintic Activity and Attenuates Hepatic Fibrosis via Modulating TGFβ1 and Akt Signaling and Shifting Th1/Th2 Balance in Schistosoma japonicum-Infected Mice

Schistosomiasis is a zoonotic and debilitating parasitic disease caused by Schistosoma japonicum. Praziquantel remains the choice for treating schistosomiasis, but its efficacy could be hampered by emergence of resistance. In this study, using large-scale drug screening, we selected out myricetin, a...

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Vydáno v:Front Immunol
Hlavní autoři: Huang, Ping, Zhou, Minyu, Cheng, Shaoyun, Hu, Yue, Gao, Minzhao, Ma, Yubin, Limpanont, Yanin, Zhou, Hongli, Dekumyoy, Paron, Cheng, Yixin, Lv, Zhiyue
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176910/
https://ncbi.nlm.nih.gov/pubmed/32373112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00593
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