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Myricetin Possesses Anthelmintic Activity and Attenuates Hepatic Fibrosis via Modulating TGFβ1 and Akt Signaling and Shifting Th1/Th2 Balance in Schistosoma japonicum-Infected Mice

Schistosomiasis is a zoonotic and debilitating parasitic disease caused by Schistosoma japonicum. Praziquantel remains the choice for treating schistosomiasis, but its efficacy could be hampered by emergence of resistance. In this study, using large-scale drug screening, we selected out myricetin, a...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Huang, Ping, Zhou, Minyu, Cheng, Shaoyun, Hu, Yue, Gao, Minzhao, Ma, Yubin, Limpanont, Yanin, Zhou, Hongli, Dekumyoy, Paron, Cheng, Yixin, Lv, Zhiyue
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176910/
https://ncbi.nlm.nih.gov/pubmed/32373112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00593
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