MicroRNA-124 negatively regulates LPS-induced TNF-α production in mouse macrophages by decreasing protein stability

AIM: MicroRNAs play pivotal roles in regulation of both innate and adaptive immune responses. In the present study, we investigated the effects of microRNA-124 (miR-124) on production of the pro-inflammatory cytokine TNF-α in lipopolysaccharide (LPS)-treated mouse macrophages. METHODS: Mouse macroph...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Sun, Yang, Qin, Zhen, Li, Qi, Wan, Jing-jing, Cheng, Ming-he, Wang, Peng-yuan, Su, Ding-feng, Yu, Jian-guang, Liu, Xia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933752/
https://ncbi.nlm.nih.gov/pubmed/27063215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.16
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