WWP1 knockout in mice exacerbates obesity‐related phenotypes in white adipose tissue but improves whole‐body glucose metabolism

White adipose tissue (WAT) is important for maintenance of homeostasis, because it stores energy and secretes adipokines. The WAT of obese people demonstrates mitochondrial dysfunction, accompanied by oxidative stress, which leads to insulin resistance. WW domain‐containing E3 ubiquitin protein liga...

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Vydáno v:FEBS Open Bio
Hlavní autoři: Hoshino, Shunsuke, Kobayashi, Masaki, Tagawa, Ryoma, Konno, Ryutaro, Abe, Takuro, Furuya, Kazuhiro, Miura, Kumi, Wakasawa, Hiroki, Okita, Naoyuki, Sudo, Yuka, Mizunoe, Yuhei, Nakagawa, Yoshimi, Nakamura, Takeshi, Kawabe, Hiroshi, Higami, Yoshikazu
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050250/
https://ncbi.nlm.nih.gov/pubmed/31965758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12795
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