WWP1 knockout in mice exacerbates obesity‐related phenotypes in white adipose tissue but improves whole‐body glucose metabolism

White adipose tissue (WAT) is important for maintenance of homeostasis, because it stores energy and secretes adipokines. The WAT of obese people demonstrates mitochondrial dysfunction, accompanied by oxidative stress, which leads to insulin resistance. WW domain‐containing E3 ubiquitin protein liga...

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Библиографические подробности
Опубликовано в: :FEBS Open Bio
Главные авторы: Hoshino, Shunsuke, Kobayashi, Masaki, Tagawa, Ryoma, Konno, Ryutaro, Abe, Takuro, Furuya, Kazuhiro, Miura, Kumi, Wakasawa, Hiroki, Okita, Naoyuki, Sudo, Yuka, Mizunoe, Yuhei, Nakagawa, Yoshimi, Nakamura, Takeshi, Kawabe, Hiroshi, Higami, Yoshikazu
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050250/
https://ncbi.nlm.nih.gov/pubmed/31965758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12795
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