Concentration Determination of >200 Proteins in Dried Blood Spots for Biomarker Discovery and Validation

The use of protein biomarkers as surrogates for clinical endpoints requires extensive multilevel validation including development of robust and sensitive assays for precise measurement of protein concentration. Multiple reaction monitoring (MRM) is a well-established mass-spectrometric method that c...

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Bibliografske podrobnosti
izdano v:Mol Cell Proteomics
Main Authors: Eshghi, Azad, Pistawka, Adam J., Liu, Jun, Chen, Michael, Sinclair, Nicholas J. T., Hardie, Darryl B., Elliott, Monica, Chen, Lei, Newman, Rachael, Mohammed, Yassene, Borchers, Christoph H.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2020
Teme:
Technological Innovation and Resources
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050112/
https://ncbi.nlm.nih.gov/pubmed/31896676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.TIR119.001820
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