Concentration Determination of >200 Proteins in Dried Blood Spots for Biomarker Discovery and Validation

The use of protein biomarkers as surrogates for clinical endpoints requires extensive multilevel validation including development of robust and sensitive assays for precise measurement of protein concentration. Multiple reaction monitoring (MRM) is a well-established mass-spectrometric method that c...

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Bibliografiske detaljer
Udgivet i:Mol Cell Proteomics
Main Authors: Eshghi, Azad, Pistawka, Adam J., Liu, Jun, Chen, Michael, Sinclair, Nicholas J. T., Hardie, Darryl B., Elliott, Monica, Chen, Lei, Newman, Rachael, Mohammed, Yassene, Borchers, Christoph H.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2020
Fag:
Technological Innovation and Resources
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050112/
https://ncbi.nlm.nih.gov/pubmed/31896676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.TIR119.001820
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