Concentration Determination of >200 Proteins in Dried Blood Spots for Biomarker Discovery and Validation

The use of protein biomarkers as surrogates for clinical endpoints requires extensive multilevel validation including development of robust and sensitive assays for precise measurement of protein concentration. Multiple reaction monitoring (MRM) is a well-established mass-spectrometric method that c...

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Dades bibliogràfiques
Publicat a:Mol Cell Proteomics
Autors principals: Eshghi, Azad, Pistawka, Adam J., Liu, Jun, Chen, Michael, Sinclair, Nicholas J. T., Hardie, Darryl B., Elliott, Monica, Chen, Lei, Newman, Rachael, Mohammed, Yassene, Borchers, Christoph H.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2020
Matèries:
Technological Innovation and Resources
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050112/
https://ncbi.nlm.nih.gov/pubmed/31896676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.TIR119.001820
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