Concentration Determination of >200 Proteins in Dried Blood Spots for Biomarker Discovery and Validation

The use of protein biomarkers as surrogates for clinical endpoints requires extensive multilevel validation including development of robust and sensitive assays for precise measurement of protein concentration. Multiple reaction monitoring (MRM) is a well-established mass-spectrometric method that c...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Proteomics
Hauptverfasser: Eshghi, Azad, Pistawka, Adam J., Liu, Jun, Chen, Michael, Sinclair, Nicholas J. T., Hardie, Darryl B., Elliott, Monica, Chen, Lei, Newman, Rachael, Mohammed, Yassene, Borchers, Christoph H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2020
Schlagworte:
Technological Innovation and Resources
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050112/
https://ncbi.nlm.nih.gov/pubmed/31896676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.TIR119.001820
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