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Rational application of targeted therapeutics in mucinous colon/appendix cancers with positive predictive factors

Molecular‐targeted therapies have demonstrated disappointing results against most advanced solid cancers. This may largey be attributed to irrational drug use against unselected cancers. We investigated the efficacy of dual MEK‐PI3K drug therapy against KRAS mutated mucin 2 (MUC2)‐secreting LS174T c...

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Publicado en:Cancer Med
Autores principales: Dilly, Ashokkumar, Honick, Brendon D., Lee, Yong J., Bartlett, David L., Choudry, Haroon A.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050077/
https://ncbi.nlm.nih.gov/pubmed/31958897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2847
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