IMPROVED CHEMOSENSITIVITY FOLLOWING MUCOLYTIC THERAPY IN PATIENT-DERIVED MODELS OF MUCINOUS APPENDIX CANCER

Abundant intraperitoneal (IP) accumulation of extracellular mucus in patients with appendiceal mucinous carcinoma peritonei (MCP) causes compressive organ dysfunction and prevents delivery of chemotherapeutic drugs to cancer cells. We hypothesized that reducing extracellular mucus would decrease tum...

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Detalhes bibliográficos
Publicado no:Transl Res
Main Authors: Dilly, Ashok K, Honick, Brendon D, Frederick, Robin, Elapavaluru, Anuleka, Velankar, Sachin, Makala, Hima, Hitchens, T Kevin, Foley, Lesley M, Guo, Jianxia, Beumer, Jan H., Rigatti, Lora Heather, Lee, Yong J, Bartlett, David L, Choudry, Haroon A
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7867596/
https://ncbi.nlm.nih.gov/pubmed/33164812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2020.10.005
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