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Synergistic apoptosis following endoplasmic reticulum stress aggravation in mucinous colon cancer
BACKGROUND: Mucinous colon cancers (MCC) are characterized by abundant production of mucin 2 (MUC2) protein and are less sensitive to standard systemic chemotherapy. We postulated that severe/persistent endoplasmic reticulum stress (ERS) aggravation in MCC would overwhelm compensatory cytoprotective...
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| Publicado no: | Orphanet J Rare Dis |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7437176/ https://ncbi.nlm.nih.gov/pubmed/32811515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-020-01499-1 |
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