Activating transcription factor 4 (ATF4) promotes skeletal muscle atrophy by forming a heterodimer with the transcriptional regulator C/EBPβ

Skeletal muscle atrophy is a highly-prevalent and debilitating condition that remains poorly understood at the molecular level. Previous work found that aging, fasting, and immobilization promote skeletal muscle atrophy via expression of activating transcription factor 4 (ATF4) in skeletal muscle fi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ebert, Scott M., Bullard, Steven A., Basisty, Nathan, Marcotte, George R., Skopec, Zachary P., Dierdorff, Jason M., Al-Zougbi, Asma, Tomcheck, Kristin C., DeLau, Austin D., Rathmacher, Jacob A., Bodine, Sue C., Schilling, Birgit, Adams, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049960/
https://ncbi.nlm.nih.gov/pubmed/31953319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.012095
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