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Generation of pre-tRNAs from polycistronic operons is the essential function of RNase P in Escherichia coli

Ribonuclease P (RNase P) is essential for the 5′-end maturation of tRNAs in all kingdoms of life. In Escherichia coli, temperature sensitive mutations in either its protein (rnpA49) and or RNA (rnpB709) subunits lead to inviability at nonpermissive temperatures. Using the rnpA49 temperature sensitiv...

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發表在:Nucleic Acids Res
Main Authors: Mohanty, Bijoy K, Agrawal, Ankit, Kushner, Sidney R
格式: Artigo
語言:Inglês
出版: Oxford University Press 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049720/
https://ncbi.nlm.nih.gov/pubmed/31993626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1188
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