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Endonucleolytic cleavages by RNase E generate the mature 3′ termini of the three proline tRNAs in Escherichia coli

We demonstrate here for the first time that proline tRNA 3′ end maturation in Escherichia coli employs a one-step endonucleolytic pathway that does not involve any of the six 3′ → 5′ exonucleases (RNase T, RNase PH, RNase D, RNase BN, RNase II and polynucleotide phosphorylase [PNPase]) to generate t...

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Publicado en:Nucleic Acids Res
Autores principales: Mohanty, Bijoy K., Petree, Jessica R., Kushner, Sidney R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291269/
https://ncbi.nlm.nih.gov/pubmed/27288443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw517
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