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The rph-1-Encoded Truncated RNase PH Protein Inhibits RNase P Maturation of Pre-tRNAs with Short Leader Sequences in the Absence of RppH

RNase PH, encoded by the rph gene, is a 3′→5′ exoribonuclease that in E. coli participates primarily in the 3′ maturation of pre-tRNAs and the degradation of rRNA in stationary-phase cells. Interestingly, the routinely used laboratory strains of MG1655 and W3110 have naturally acquired the rph-1 all...

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Библиографические подробности
Опубликовано в: :J Bacteriol
Главные авторы: Bowden, Katherine E., Wiese, Nicholas S., Perwez, Tariq, Mohanty, Bijoy K., Kushner, Sidney R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648866/
https://ncbi.nlm.nih.gov/pubmed/28808133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00301-17
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