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Contribution of Trough Concentration Data in the Evaluation of Multiple-Dose Pharmacokinetics for Drugs with Delayed Distributional Equilibrium and Long Half-Life

PURPOSE: The performance of “trough sampling before reaching steady-state” and “serial sampling beyond the interval between steady-state” in a multiple-dose pharmacokinetic evaluation was compared. Drugs with long half-lives, following multi-compartment pharmacokinetics, and whose distribution-relat...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Drug Des Devel Ther
Päätekijät: Choi, Suein, Jeon, Sangil, Yim, Dong-Seok, Han, Seunghoon
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Dove 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049277/
https://ncbi.nlm.nih.gov/pubmed/32158198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S236701
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