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Exploring the interplay between fibrillization and amorphous aggregation channels on the energy landscapes of tau repeat isoforms
Filaments made up of different isoforms of tau protein are associated with a variety of neurodegenerative diseases. Filaments made up of the 4R-tau isoform, which has four repeat regions (R1 to R4), are found in patients suffering from Alzheimer’s disease, while filaments made of the 3R-tau isoform,...
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| Gepubliceerd in: | Proc Natl Acad Sci U S A |
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| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7049151/ https://ncbi.nlm.nih.gov/pubmed/32029593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1921702117 |
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