MitoPark Transgenic Mouse Model Recapitulates the Gastrointestinal Dysfunction and Gut-Microbiome Changes of Parkinson’s Disease

Gastrointestinal (GI) disturbances are one of the earliest symptoms affecting most patients with Parkinson’s disease (PD). In many cases, these symptoms are observed years before motor impairments become apparent. Hence, the molecular and cellular underpinnings that contribute to this early GI dysfu...

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Udgivet i:Neurotoxicology
Main Authors: Ghaisas, Shivani, Langley, Monica R, Palanisamy, Bharathi N, Dutta, Somak, Narayanaswamy, Kirthi, Plummer, Paul J, Sarkar, Souvarish, Ay, Muhammet, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7048412/
https://ncbi.nlm.nih.gov/pubmed/31505196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2019.09.004
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