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MUC1 Negatively Regulates GalNAc Transferase 5 Expression in Pancreatic Cancer

Aberrant expression of MUC1 glycoprotein has been associated with pancreatic cancer (PC) progression and metastasis and mediates oncogenic transcriptional regulation of target genes during the disease progression. Here, we demonstrate that MUC1 downregulates the tumor suppressor function associated...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Caffrey, Thomas, Sagar, Satish, Thomas, Divya, Lewallen, Michelle E, Hollingsworth, Michael A, Radhakrishnan, Prakash
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7048170/
https://ncbi.nlm.nih.gov/pubmed/31283009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13532
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