Toddalolactone Protects Lipopolysaccharide-Induced Sepsis and Attenuates Lipopolysaccharide-Induced Inflammatory Response by Modulating HMGB1-NF-κB Translocation

Toddalolactone (TA-8) is a main compound isolated from Toddalia asiatica (L.) Lam., and its anti-inflammatory activity and anti-inflammatory mechanism are less studied. In the present study, we investigated the anti-inflammatory effects of TA-8. Our experimental results showed that TA-8 inhibited th...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Ni, Jingyu, Zhao, Yuxuan, Su, Jing, Liu, Zhihao, Fang, Shiming, Li, Lan, Deng, Jie, Fan, Guanwei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047824/
https://ncbi.nlm.nih.gov/pubmed/32153412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00109
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