IL-1-mediated sex differences in Kawasaki Disease vasculitis development and response to treatment

OBJECTIVE: Kawasaki Disease (KD) is the leading cause of acute vasculitis and acquired heart disease in children in developed countries. Notably, KD is more prevalent in males than females. We previously established a key role for IL-1 signaling in KD pathogenesis, but whether this pathway underlies...

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Udgivet i:Arterioscler Thromb Vasc Biol
Main Authors: Porritt, Rebecca A., Markman, Janet L., Maruyama, Daisuke, Kocaturk, Begum, Chen, Shuang, Lehman, Thomas J. A., Lee, Youngho, Fishbein, Michael C, Rivas, Magali Noval, Arditi, Moshe
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047651/
https://ncbi.nlm.nih.gov/pubmed/31996019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.119.313863
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