Inhibition of IL-6 in the LCWE Mouse Model of Kawasaki Disease Inhibits Acute Phase Reactant Serum Amyloid A but Fails to Attenuate Vasculitis

OBJECTIVE: Kawasaki disease (KD) is the most common cause of acquired pediatric heart disease in the developed world. 10% of KD patients are resistant to front-line therapy, and no interventions exist to address secondary complications such as myocardial fibrosis. We sought to identify proteins and...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Porritt, Rebecca A., Chase Huizar, Carol, Dick, Edward J., Kumar, Shyamesh, Escalona, Renee, Gomez, Angela C., Marek-Iannucci, Stefani, Noval Rivas, Magali, Patterson, Jean, Forsthuber, Thomas G., Arditi, Moshe, Gorelik, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8064710/
https://ncbi.nlm.nih.gov/pubmed/33897686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.630196
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