IL-1-mediated sex differences in Kawasaki Disease vasculitis development and response to treatment

OBJECTIVE: Kawasaki Disease (KD) is the leading cause of acute vasculitis and acquired heart disease in children in developed countries. Notably, KD is more prevalent in males than females. We previously established a key role for IL-1 signaling in KD pathogenesis, but whether this pathway underlies...

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Veröffentlicht in:Arterioscler Thromb Vasc Biol
Hauptverfasser: Porritt, Rebecca A., Markman, Janet L., Maruyama, Daisuke, Kocaturk, Begum, Chen, Shuang, Lehman, Thomas J. A., Lee, Youngho, Fishbein, Michael C, Rivas, Magali Noval, Arditi, Moshe
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047651/
https://ncbi.nlm.nih.gov/pubmed/31996019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.119.313863
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