Thyrotropin, but Not Thyroid-Stimulating Antibodies, Induces Biphasic Regulation of Gene Expression in Human Thyrocytes

Background: Thyrotropin (TSH) and thyroid-stimulating antibodies (TSAbs) activate TSH receptor (TSHR) signaling by binding to its extracellular domain. TSHR signaling has been studied extensively in animal thyrocytes and in engineered cell lines, and differences in signaling have been observed in di...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Thyroid
Hlavní autoři: Jang, Daesong, Morgan, Sarah J., Klubo-Gwiezdzinska, Joanna, Banga, J. Paul, Neumann, Susanne, Gershengorn, Marvin C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc., publishers 2020
Témata:
Thyroid Economy: Regulation, Cell Biology, and Thyroid Hormone Metabolism and Action
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047096/
https://ncbi.nlm.nih.gov/pubmed/31805824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2019.0418
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky