Thyrotropin, but Not Thyroid-Stimulating Antibodies, Induces Biphasic Regulation of Gene Expression in Human Thyrocytes

Background: Thyrotropin (TSH) and thyroid-stimulating antibodies (TSAbs) activate TSH receptor (TSHR) signaling by binding to its extracellular domain. TSHR signaling has been studied extensively in animal thyrocytes and in engineered cell lines, and differences in signaling have been observed in di...

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Detalhes bibliográficos
Publicado no:Thyroid
Main Authors: Jang, Daesong, Morgan, Sarah J., Klubo-Gwiezdzinska, Joanna, Banga, J. Paul, Neumann, Susanne, Gershengorn, Marvin C.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2020
Assuntos:
Thyroid Economy: Regulation, Cell Biology, and Thyroid Hormone Metabolism and Action
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047096/
https://ncbi.nlm.nih.gov/pubmed/31805824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2019.0418
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