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Suboptimal Stimulation by Weak Agonist Epitope Variants Does Not Drive Dysfunction of HIV-1-Specific CTL Clones
OBJECTIVE: To assess whether weakly recognized epitope variants induce anergy in HIV-1-specific CD8(+) T lymphocyte (CTL) clones as a mechanism of dysfunction. DESIGN: HIV-1-specific CTL clones were exposed to suboptimally recognized epitope variants, and screened for anergy and other T cell dysfunc...
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| Vydáno v: | AIDS |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7046083/ https://ncbi.nlm.nih.gov/pubmed/31306165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000002259 |
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