Diversity of escape variant mutations in Simian virus 40 Large Tumor Antigen (SV40 T ag) epitopes selected by cytotoxic T lymphocyte (CTL) clones

To better understand the relationship between epitope variation and tumor escape from immune surveillance, SV40 T antigen transformed B6/K-0 cells were subjected to selection with individual CTL clones specific for the SV40 T antigen H-2D(b)-restricted epitopes I or V. CTL resistant populations were...

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Hauptverfasser: Mylin, Lawrence M., Schell, Todd D., Epler, Melanie, Kusuma, Carolyn, Assis, David, Matsko, Chelsea, Smith, Alexandra, Allebach, April, Tevethia, Satvir S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866617/
https://ncbi.nlm.nih.gov/pubmed/17368499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.02.007
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