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Nef interference with HIV-1–specific CTL antiviral activity is epitope specific
HIV-1 Nef and HIV-1–specific cytotoxic T lymphocytes (CTLs) have important and opposing roles in the immunopathogenesis of HIV-1 infection. Nef-mediated down-modulation of HLA class I on infected cells can confer resistance to CTL clearance, but the factors determining the efficiency of this process...
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主要な著者: | , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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The American Society of Hematology
2006
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895430/ https://ncbi.nlm.nih.gov/pubmed/16882705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-06-030668 |
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