Nef interference with HIV-1–specific CTL antiviral activity is epitope specific

HIV-1 Nef and HIV-1–specific cytotoxic T lymphocytes (CTLs) have important and opposing roles in the immunopathogenesis of HIV-1 infection. Nef-mediated down-modulation of HLA class I on infected cells can confer resistance to CTL clearance, but the factors determining the efficiency of this process...

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Detalhes bibliográficos
Main Authors: Adnan, Sama, Balamurugan, Arumugam, Trocha, Alicja, Bennett, Michael S., Ng, Hwee L., Ali, Ayub, Brander, Christian, Yang, Otto O.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2006
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895430/
https://ncbi.nlm.nih.gov/pubmed/16882705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-06-030668
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