A carregar...

Epitope targeting and viral inoculum are determinants of Nef-mediated immune evasion of HIV-1 from cytotoxic T lymphocytes

The impact of HIV-1 Nef-mediated HLA-I down-regulation on CD8(+) cytotoxic T lymphocytes (CTLs) varies by epitope, but the determining factors have not been elucidated. In the present study, we investigated the impact of Nef on the antiviral efficiency of HIV-1–specific CTLs targeting 17 different e...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chen, Diana Y., Balamurugan, Arumugam, Ng, Hwee L., Cumberland, William G., Yang, Otto O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390950/
https://ncbi.nlm.nih.gov/pubmed/22613796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-409870
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!