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Gastrointestinal motility, dysbiosis and opioid-induced tolerance: is there a link?
Studies show that gut microbial dysbiosis induced by chronic opioid use is linked to central opioid tolerance. Here, we suggest that a persistent decrease in gastrointestinal motility by opioids is a primary cause of gut microbial dysbiosis and that improving gastrointestinal transit might be a stra...
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| Udgivet i: | Nat Rev Gastroenterol Hepatol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7045338/ https://ncbi.nlm.nih.gov/pubmed/31024090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41575-019-0150-x |
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