Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome

During adult hippocampal neurogenesis, most newborn cells undergo apoptosis and are rapidly phagocytosed by resident microglia to prevent the spillover of intracellular contents. Here, we propose that phagocytosis is not merely passive corpse removal but has an active role in maintaining neurogenesi...

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Publicado en:J Neurosci
Main Authors: Diaz-Aparicio, Irune, Paris, Iñaki, Sierra-Torre, Virginia, Plaza-Zabala, Ainhoa, Rodríguez-Iglesias, Noelia, Márquez-Ropero, Mar, Beccari, Sol, Huguet, Paloma, Abiega, Oihane, Alberdi, Elena, Matute, Carlos, Bernales, Irantzu, Schulz, Angela, Otrokocsi, Lilla, Sperlagh, Beata, Happonen, Kaisa E., Lemke, Greg, Maletic-Savatic, Mirjana, Valero, Jorge, Sierra, Amanda
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2020
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044727/
https://ncbi.nlm.nih.gov/pubmed/31896673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0993-19.2019
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