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A simulation model of neuroprogenitor proliferation dynamics predicts age-related loss of hippocampal neurogenesis but not astrogenesis

Adult hippocampal neuroprogenitors give rise to both neurons and astrocytes. As neuroprogenitors are lost with increased age, neurogenesis concomitantly decreases. However, the dynamics of neuron and astrocyte generation throughout adulthood has not been systematically examined. Here, we analyzed th...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Beccari, Sol, Valero, Jorge, Maletic-Savatic, Mirjana, Sierra, Amanda
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705784/
https://ncbi.nlm.nih.gov/pubmed/29184142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16466-3
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