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HIV protease cleaves the antiviral m(6)A reader protein YTHDF3 in the viral particle
N(6)-methyladenosine (m(6)A) is the most abundant HIV RNA modification but the interplay between the m(6)A reader protein YTHDF3 and HIV replication is not well understood. We found that knockout of YTHDF3 in human CD4+ T-cells increases infection supporting the role of YTHDF3 as a restriction facto...
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| Veröffentlicht in: | PLoS Pathog |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7043784/ https://ncbi.nlm.nih.gov/pubmed/32053707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008305 |
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