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SOX4: The Unappreciated Oncogene
SOX4 is an essential developmental transcription factor that regulates stemness, differentiation, progenitor development, and multiple developmental pathways including PI3K, Wnt, and TGFβ signaling. The SOX4 gene is frequently amplified and overexpressed in over 20 types of malignancies, and multipl...
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| Publicado no: | Semin Cancer Biol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7043201/ https://ncbi.nlm.nih.gov/pubmed/31445218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2019.08.027 |
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