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Evidence That SOX2 Overexpression Is Oncogenic in the Lung
BACKGROUND: SOX2 (Sry-box 2) is required to maintain a variety of stem cells, is overexpressed in some solid tumors, and is expressed in epithelial cells of the lung. METHODOLOGY/PRINCIPAL FINDINGS: We show that SOX2 is overexpressed in human squamous cell lung tumors and some adenocarcinomas. We ha...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2883553/ https://ncbi.nlm.nih.gov/pubmed/20548776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011022 |
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