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Treg-Cell-Derived IL-35-Coated Extracellular Vesicles Promote Infectious Tolerance
Interleukin-35 (IL-35) is an immunosuppressive cytokine composed of Epstein-Barr-virus-induced protein 3 (Ebi3) and IL-12α chain (p35) subunits, yet the forms that IL-35 assume and its role in peripheral tolerance remain elusive. We induce CBA-specific, IL-35-producing T regulatory (Treg) cells in T...
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| Udgivet i: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7042971/ https://ncbi.nlm.nih.gov/pubmed/31995748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.12.081 |
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